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Why Can Anemia Happen to PKD Patients and Its Best Treatment

2013-09-07 15:28

anemia, PKDAnemia is likely to happen to PKD patients and then cause a series of symptoms like fatigue, poor appetite, insomnia and even depressive state, which discounts the quality of life and influences the prognosis of the condition. Now follow us to learn more about anemia and PKD.

Why can anemia happen to PKD patients?

The enlargement of cysts growing on kidneys can gradually oppress the surrounding kidney tissues, which makes kidneys ischemic and anoxic. If the condition can not be relived in time, impaired kidney function will happen, leading to anemia and other symptoms and complications.

If impaired renal function appears in PKD patients, wastes and toxins can not be removed out of body normally, they will build up in the body. The accumulation of harmful substances can cause the relative lack in EPO which tells the marrow to produce red blood cells, then the production of red blood cells can be reduced, and anemia appears. Kidney disease patients are commonly suggested to keep a low-protein diet, the occurrence rate of malnutrition can reach up to 30%-60%, which causes the insufficient of hematopoietic raw material. The harmful substances in PKD patients’ body can also shorten the life span of red blood cells. For common people, the average lifespan of red blood cells is about 120d, while for kidney failure patients, the average lifespan of red blood cells is declined to about 40-60d.

The best treatment for anemia in PKD patients

If your anemia is due to kidney damage, in the clinic, you will be commonly treated with drugs called erythropoiesis stimulating agents (ESAs) and extra iron. However, if PKD patients want to treat anemia from the root, these measures seem to be not enough.

The best treatment for anemia and other symptoms of PKD is to treat the disease from the root. In that case, the most important things are to shrink cysts and recover renal function. Moreover, the safety should also be taken into consideration. If you want to know what treatments are commonly used in clinic to help recover renal function, leave a message below or send us an email to

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