What is the best treatment for SLE and chronic kidney disease? SLE is a common autoimmune disease which is likely to damage skin, heart, lungs, brain and kidneys and other organs in the body. Lupus nephritis means the kidney inflammation caused by SLE. If the condition can not be controlled well, it gradually develops chronic kidney disease.
60% of people with SLE will develop lupus nephritis and about 30% of lupus nephritis patients may develop kidney failure after 5-20 years. For lupus nephritis patients, those immune complexes depositing on the glomerular epithelial cells can cause the immuno-inflammatory responses. During the battle between the foreign bodies, the damage to kidneys will not be unavoidable. Gradually the charge barrier of glomerular epithelial cell will be damaged, which causes protein in the urine and other symptoms. If the damage to glomeruli can not be repaired in time, the kidney function will be gradually lost. According to glomerular filtration rate (GFR) level, chronic kidney disease can be divided into five stages. In general, stage 3 chronic kidney disease still can be reversed by an efficient treatment. Once the condition develops stage 4 chronic kidney disease, this possibility will be discounted.
Immunotherapy is regarded as the best treatment for SLE and chronic kidney disease. This treatment is a systemic therapy which includes six steps. In immune clearance, plasma exchange, a common blood purification technique, will be used to help eliminate lupus in the blood, which stops further damage to kidneys and other organs in the body. In immune adjustment and immune protection, Chinese herbal medicines can play a series of functions to help repair kidney damage and recover renal function, which prevents chronic kidney disease developing kidney failure. Moreover, all the Chinese herbal medicines come from the nature, so patients do not need to worry about the side effects.
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