In our daily life, most people may think that the normal creatinine level indicates the kidney health. But in fact they don’t know that when the patients have some obvious symptoms, they had already experienced the kidney lesion, and the more important thing is that the creatinine begins to rise, so the patients should pay more attention to the creatinine in their life. However, what cause the high creatinine?
First, the creatinine is one of the indicators of the kidney function. In general, creatinine is removed from the blood chiefly by the kidney, primarily by glomerular filtration. Most serum creatinine is removed out of the body via urine. The concentration of creatinine blood depends on glomerular filtration function. If there is something wrong with the kidney, it will no longer filter creatinine from the blood effectively, at this time, creatinine levels will rise until about forty percent of kidney function has already been out of work. Generally, healthy people will have a constant level of creatinine over time. Men typically have a higher concentration than women, because they have more muscle tissue. Vegetarians and the elderly frequently have lower levels of this compound. The higher creatinine levels indicate the poor kidney function. So for a patient, the doctor can trace his creatinine level to help confirm the kidney disease. By watching their creatinine levels change, the doctors or experts can get a general sense of how the kidney disease progressing.
Second, dehydration or inadequate water intake such as high fever, sweating, diuresis can cause blood concentration and reduced blood flow in the kidneys. Then the creatinine will increase.
Third, both high blood pressure and diabetes can also cause high creatinine level. For the high blood pressure, it damages the kidney’s small blood vessels, so that which can not filter the waste properly. This can be treated with ACE inhibitors, which may in return result in elevated creatinine levels. Some common medication, like over-the-counter painkillers can also cause elevated creatinine level if taken for too long.
So when you are diagnosed as high creatinine, you must find the primary disease and receive the correct treatment, in order to avoid the change from the high creatinine to the uremia.
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