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Creatinine Levels And Kidney Disease Stages

2013-05-31 14:38

In clinic, many indicators can be used to measure kidney function like creatinine level, GFR(Glomerular Filtration Rate) and stages. For some kidney disease patients, they may know their creatinine level, but have no ideal about what stage their kidney problem is in. However, for some others, they may well about what stage their kidney disease has run to, but know nothing about their GFR. Is there any relationship between them?

Here, we will give an introduction about interrelation of kidney disease stages, creatinine levels and GFR:

Stage one: For people with kidney disease in stage one, their GFR is no less than 90ml/min/1.73m2 which is considered as a normal value. However, through medical tests, abnormal pathological changes, blood component and kidney imagine can be found. Besides, serum creatinine level stays in the normal range (50-140umol/L) in stage one kidney disease.

Stage two: Stage two kidney disease is typically marked by GFR 60-89ml/min/1.73m2 and mildly decreased kidney function. For people with stage 2 kidney disease, there is no obvious increase of their serum creatinine level and it is usually lower than 177 umol/L.

Stage three: For kidney disease patients whose serum creatinine level is in the range 178-442umol/L, their GFR usually fluctuates in the range 30-59ml/min/1.73m2 which means kidney function has a moderate decrease.

Stage four: Stage 4 kidney disease can be regarded as kidney failure stage which is characterized by serious decrease of kidney function. For people with stage 4 kidney disease, their GFR has decreased to the range 15-29ml/min/1.73m2. And under such a condition, their serum creatinine is much higher than the normal range and usually has increased to the range of 442-707umol/L.

Stage 5: Stage 5 kidney disease is commonly known as End Stage Renal Disease (ESRD) or end stage kidney failure. In such a case, patients’ GFR is no more than 15 and what is worse, their creatinine level has increased to the level more than 707umol/L which needs patients to do dialysis or kidney transplant.

Chronic Kidney Disease is the progressive loss of kidney function. Different creatinine level and GFR means there are different residual kidney function and we need to take different medical measures to deal with it.

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