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Focal Segmental Glomerulosclerosis and Kidney Transplant

2013-09-14 09:52

Focal Segmental Glomerulosclerosis is a rare disease that attacks the glomeruli causing serious scarring. About half of FSGS patients who do not respond to steroids go into ESRD each year, requiring dialysis or kidney transplant. Now let’s learn more about Focal Segmental Glomerulosclerosis and kidney transplant.

In FSGS, the success of kidney transplant may be impaired by the frequent risk of recurrence of the disease on the allograft and by the poor graft survival rate in patients with recurrence. In the first kidney transplant, about 20 to 30% of patients develop recurrence of FSGS. A number of factors have been reported to be associated with an increased risk of recurrence. Second kidney transplant, in those who have had recurrence in their first graft, are generally accompanied by a further recurrence. Young children, patients with mesangial proliferation in the native kidneys, patients who had a rapid progression to ESRD, those who received the kidney from an older donor have been reported to have a higher risk of recurrence.

Generally speaking, Focal Segmental Glomerulosclerosis has a high relapse rate after kidney transplant and it can even reach up to 50%. But some FSGS patients who received a kidney transplant are likely to live for more than 20 or more years.

Even though your Focal Segmental Glomerulosclerosis develops End Stage Renal Disease, it does not mean kidney transplant will be the last choice. An efficient FSGS treatment means the one which has the ability to play three functions and they are eliminating immune complexes; recovering renal function and adjusting immune system. Only through this, kidney transplant can be effectively avoided.

You can click The Newest FSGS Treatment: Immunotherapy to learn more about other treatment option, which is expected to bring you new hopes. Any follow-up questions, you are welcomed to leave a message below or consult online doctor freely.

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