Kidney failure is regarded as the final consequence of IgA Nephropathy by many people, as IgA Nephropathy can not be cured now and always progresses over time in many cases. However, this does mean all the IgA Nephropathy patients will develop kidney failure at last and in reality, kidney failure patients can be avoided by IgA Nephropathy patients.
How does IgA Nephropathy progress to kidney failure?
IgA Nephropathy is an autoimmune disease marked by large amounts of IgA immune complexes in mesangial area. It is regarded as an autoimmune disease, because occurrence of it is closely related with immune system.
IgA stands for immunoglobulin A which is an antibody of our body. When IgA immune complexes are formed and deposit in kidney, inflammation will occur. Inflammation helps us remove immune complexes, but unfortunately, it can damage surrounding kidney tissues too. Without effective clearnce of IgA immune complexes, inflammation lasts and more and more kidney tissues are damaged. In this way, IgA Nephropathy progresses gradually.
How to avoid kidney failure with IgA Nephropathy?
To stop IgA Nephropathy from progressing to kidney failure, the following steps are necessary:
1. Block inflammation: inflammation is the direct cause of kidney damages, so to avoid further kidney damages, inflammation must be blocked immediately and effectively.
2. Remove IgA immune complexes in mesangial area: For IgA Nephropathy patients, they can take some immunosuppressive agents to block inflammation, but the treatment effect is temporary. As long as IgA immune complexes in mesangial area are not removed, inflammation will occur again someday. Therefore, if IgA Nephropathy patients want to avoid further kidney damages radically, removing IgA immune complexes away from mesangial area is a must.
3. Normalize immune system and increase immunity: we can live normally without being affected by surrounding bacterium and viruses owing to our strong immune system. For IgA Nephropathy patients, antigen invade their body because of immunodeficiency and poor immunity. By normalizing immune system and increasing immunity, IgA immune complexes can be prevented. When no IgA immune complexes are formed, no inflammation occurs and also no further kidney damages are caused any more.
4. Beneficial diet: A beneficial diet will protect illness condition from being worsened. For IgA Nephropathy patients, beneficial diet refers to low-protein diet, low-salt diet, low-potassium diet, high-calcium diet and high-vitamin diet.
The above 4 medical measures are essential for IgA Nephropathy patients to avoid kidney failure and if there is anything unclear, please leave message to us directly.
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