Immunoadsorption is one of the dominant blood purification technologies and mainly applied to remove antibody, immune complexes and some other pathogentic factors from the blood with some kind of adsorbent. Different from many other blood purification technologies, Immunoadsorption allows not only a more specific but also a more effective clearance of circulating harmful substances in the blood.
In clinic, the basic operation procedure of Immunoadsorption can be described as following:
Firstly, take blood out of patient's body and build an extracorporeal system, during which, anticoagulation measures are needed.
Secondly, remove plasma from blood with the help of Plasma-Flow.
Thirdly, lead plasma to a medical machine in which pathogentic factors are reabsorbed by adsorbent in selective way.
Forth, purified blood is returned to patient's body.
Immunoadsorption shows great treatment effects in the following several aspects:
1. Removal of pathologenic factors
As a matter of fact, many diseases can be attributed to circulating pathologenic factors like autoimmune antibodies, circulating immune complexes, tumor necrosis factors, interleukin, low density lipoprotein, circulating toxins and endotoxin and so on.
2. Removal of anaphylatoxin
Removal of anaphylatoxin is very helpful for delaying inflammatory reaction and influence of cell factor.
3. Regulating immune system
Immunoadsorption helps to regulate patient's immune system by decreasing the synthesis of interleukin-1 and interleukin-6 as well as reducing the release of inflammatory mediators.
In clinic, Immunoadsorption can be used to treat many diseases like kidney diseases, organ transplantation, blood diseases, nerve system diseases and rheumatic disease. As Immunoadsorption shows quick and obvious treatment effects in regulating immune system and removing pathologenic factors in blood, among its indicatons, Immunoadsorption is especially effective in treating SLE (Systemic Lupus Erythematosus), a kind of autoimmune disease.
Although Immunoadsorption plays an important role in purifying blood, its treatment effects are temporary, so it is usually used together with some oral medicines. Besides, as improper application of Immunoadsorption may bring side effects, so while appling Immunoadsorption, a close observation is necessary.
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