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Why Creatinine Elevates After Kidney Transplant

2013-01-30 10:56

It is not uncommon that many kidney transplant patients will once again have elevated creatinine level and many of them will start dialysis years or even weeks after the surgery.

Before solving the issue, we should know that many kidney transplant patients can not have normal creatinine level even after the surgery especially for those that have bilateral renal parenchymal diseases because both their kidneys have been damaged and the transplanted kidney can only enable 50% kidney functions.

If creatinine is higher than 2 and it has the tendence to further increase, it means problems of the transplanted kidney. Patients should first make clear the underlying cause and seek timely measures to bring the creatinine low, prevent further renal damages and prolong the life span of the transplanted kidney.

There are many reasons that can cause high creatinine after kidney transplant. Organ rejection and various infections are the common ones.

Organ rejection

Organ rejection is very common among kidney transplant patients and that is why it is extremely important to find a matching donor to help improve the success rate of this surgery. There are many reported cases that creatinine once again elevate a period after the transplantation due to organ rejection. Besides, high creatinine level, patients may also have high blood pressure, proteinuria and decline of kidney functions.

If high creatinine is confirmed to be caused by rejection of the newly settled kidney, report it to the doctors. According to the severity of rejection, patients need to adjust the dosage of anti-rejection drugs or change for other more powerful medicines.

Various infections

Kidney disease patients already have low immunity and the intake of anti-rejection medicines will further suppress their immune system and lower their immunity. As a result, patients are more susceptible to various infections after kidney transplant and the infections are easy to damage their transplant kidney and induce the relapse of kidney damages.

The following are some tips for bringing down the elevated creatinine and help kidney transplant patients to avoid dialysis.

Proper diets. Low-protein, low-fat, low-salt diets are good for reducing high creatinine level and protecting the transplanted kidney.

Well control of high blood pressure and blood sugar and effective treatment for proteinuria are very crucial for slowing down decline rate of kidney functions. ACEI and ARB medicines are effective at reducing proteinuria, controlling high blood pressure and protecting kidney functions.

Lowering blood lipid level, anti-coagulation and improvement of blood flow to the kidneys are also very good for prolonging life expectancy of the transplanted kidney.

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