A study has been published in American Journal of Transplantation and it reported 73.5% live birth rate for having a successful pregnancy after receiving kidney transplantation. That is to say, it is possible for kidney transplant recipients to have babies successfully and here the recipients refer to women.
We know that women that have kidney disease should have more cautions to decide to have pregnancy because it will increase burdens to gravida's kidneys, heart and other organs and will easily induce the relapse of kidney disease.
As for those that have received a transplanted kidney, it is usually not recommended to have pregnancy for the safety of both the mother and baby. Women after kidney transplant have relatively high risk of developing pregnancy complications such as preterm delivery, gestational diabetes and preeclampsia, etc.
The new study brings hope for many women of childbearing age. What is more, the pregnancy complications rate will fall to 50% if the interval between pregnancy and kidney transplant is more than 2 years and less than 5 years.
However, that does not mean the risk has gone away. The risk still exists, the significance of the study is to tell women after kidney transplant that successful pregnancy is possible. The next step is to find how to increase the successful rate of pregnancy and reduce the risk of pregnancy complications.
Usually it takes about 6 months for female patients to restore ovulation, menstruation and sexuality after kidney transplant with the recovery of kidney functions. Under the following conditions, they can prepare for pregnancy.
1. Renal function is stable 18 months after the transplantation and the physical condition is good;
2. Serum creatinine is lower than 2mg/dl;
3. There is no high blood pressure and proteinuria;
4. Small dosage of maintenance immunosuppressant;
5. There is no water or expansion in calyces and renal pelvis;
It is recommended the interval between pregnancy and kidney transplant should be 2-5 years. The risk of acute rejection and loss of the transplanted kidney is high within the first 2 years and there will be more chronic rejections after 5 years.
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