Resources: Creatinine | Treatment | Experts

Call Us for More Information

Contact Us | About Hospital

Home > News and Research >

Donor-specific Antibodies Increase Rejection in Kidney Transplant

2012-12-07 16:58

It has been found by a study performed by doctors from Columbia University Medical Center that even very low level of donor-specific antibodies will increase the risk of organ rejections and kidney failure after the transplantation. The antibody-mediated rejection and kidney failure is almost doubled.

If the transplant recipients have had transplant operation or blood transfusion before, they often have certain antibodies that are against particular donor's kidneys which is better be avoided if more matching donors are available. These antibodies are called donor-specific antibodies.

It is hard to detect these antibodies with traditional tests. Some new tests called solid phase assays can find them even when their blood concentrations are very low.

So what is the significance of this study and finding? We know that the organ rejection is one major concern of many renal failure patients waiting for kidney transplant as well as the doctors. Patients have to take anti-rejection medicines for the rest of their life and suffer from suppressed immunity. What is more, the transplanted kidney has risk of failing once again. This study can help clinicians have better and more suitable matching of kidney donor and recipients. It can also help clinicians prescribe more effective immunosuppressant and reduce rejections after the surgery so as to increase the successful and survival rate of transplanted kidney.

Leave Message

Leave your problem to us,You will surely get the free medical advice from experts within 24 hours!

Name :
E-mail :
Subject :

Related articles

Who Gives me the Second Choice to Live

It is daddy and mommy who sacrifice their life and help me lived for 17 years. And I need to do something to give it back, said Jane who...More

Happy Mid-Autumn Festival in Shijiazhuang Kidney Disease Hospital

Falling on the 15th day of the 8th mouth according to Chinese lunar calender, Mid Autumn Festival is one of traditional festivals in Chi...More

Arabian Celebrated Eid al-Fitr in Shijiazhuang Kidney Disease Hospital

A great number of Muslims celebrated Eid al-Fitr a festival, marking the end of the hole month of Ramadan. Many people who are suffering...More

Chronic Renal Failure


facebook twitter rss tel

Contact Us

Email :

Tel :


facebook :

Free solutions