Resources: Creatinine | Treatment | Experts

Call Us for More Information

Contact Us | About Hospital

Home > News and Research >

Donor-specific Antibodies Increase Rejection in Kidney Transplant

2012-12-07 16:58

It has been found by a study performed by doctors from Columbia University Medical Center that even very low level of donor-specific antibodies will increase the risk of organ rejections and kidney failure after the transplantation. The antibody-mediated rejection and kidney failure is almost doubled.

If the transplant recipients have had transplant operation or blood transfusion before, they often have certain antibodies that are against particular donor's kidneys which is better be avoided if more matching donors are available. These antibodies are called donor-specific antibodies.

It is hard to detect these antibodies with traditional tests. Some new tests called solid phase assays can find them even when their blood concentrations are very low.

So what is the significance of this study and finding? We know that the organ rejection is one major concern of many renal failure patients waiting for kidney transplant as well as the doctors. Patients have to take anti-rejection medicines for the rest of their life and suffer from suppressed immunity. What is more, the transplanted kidney has risk of failing once again. This study can help clinicians have better and more suitable matching of kidney donor and recipients. It can also help clinicians prescribe more effective immunosuppressant and reduce rejections after the surgery so as to increase the successful and survival rate of transplanted kidney.

Leave Message

Leave your problem to us,You will surely get the free medical advice from experts within 24 hours!

Name :
E-mail :
Subject :

Related articles

Shjiazhuang Kidney Disease Hospital was Invited to Attend the National Day Reception by UAE Embassy

29th November, UAE(United Arab Emirates) embassy held a National Day reception in Beijing to celebrate 45th anniversary. Muhammad Shamus...More

Shijiazhuang Kidney Disease Hospital Signs Clinical Collaboration Agreement with India Apollo Hospital

Wanting to help more kidney failure patients worldwide, Shijiazhuang Kidney Disease Hospital decided to have a medical academic exchange...More

Director of Islam Church Visited Shijiazhuang Kidney Disease

On 8th October, director of Islam Church visited Shijiazhuang Kidney Disease Hospital which is a hospital specialized in treating kidney...More

kidney failure

Renal Failure Treatment


facebook twitter rss tel