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Chronic Renal Failure and Erythropoietin (EPO)

2013-05-09 10:08

Erythropoietin (EPO) is a hormone mainly made by the kidneys and tells stem cells in the bone marrow to make more red blood cells. In chronic renal failure, less erythropoietin is produced so that patients are more likely to have fatigue and anemia. Therefore, knowing the link of chronic renal failure and erythropoietin is good for these patients.

How is kidney failure associated to erythropoietin?

In healthy kidneys, the kidney cells that make erythropoietin are specialized so that they are sensitive to low oxygen levels in the blood. When anemia, low red blood cell, and other complications due to low oxygen level occur, the healthy kidney cells can produce more EPO so that these complications can be remitted spontaneously. However, once the kidneys are damaged severely, they can’t make enough EPO any more and then the above symptoms like anemia may occur easily.

EPO, in turn, can also worsen kidney failure patients’ condition, because lack of red blood cells leads to less blood and oxygen transported into the kidneys and then more than more kidney cells lose their ability to work gradually.

How to deal with lack of erythropoietin in chronic renal failure?

A healthy diet rich in nutrition and iron and correct medicines can be helpful. For people with kidney failure and severe anemia, erythropoietin is usually given by subcutaneous injection initially three times a week in conjunction with an oral iron supplement. The does of medicines changes with patients’ red blood cell count test. Generally, patients’ erythropoietin problem can be controlled very well after the treatment.

However, even though these medicines can help ease anemia and fatigue as well as some other complications, patients’ damaged kidneys can’t get any improvement. To increase patients’ overall health, repairing impaired kidney cells is a must. Two remedies can help achieve this goal: Micro-Chinese Medicine Osmotherapy and Immunotherapy. Both of them have their own application scope, so you should choose a better treatment according to your specific condition.

Once part of kidney function recovers to work again, it can produce enough EPO by itself so that you won’t take any medicines to stimulate the formation of red blood cells. If any confusion, you can leave a message to us or consult online.

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